As a mixer you want to draw the listener’s attention in at specific moments of a song. You can do this in a variety of ways of course, but one that I find super helpful is to play with octaves of guitar parts.
Pitch That Sucker Down
A quick way to emphasize a guitar part is to select part of it, copy it, and pitch it down an octave. Sure it won’t sound natural, but if you bury it just under the original it can thicken up your guitar work very nicely.